Luana Colloca, MD, PhD, MS

Luana Colloca, MD, PhD, MS
  • Associate Professor
    Pain and Translational Symptom Science

Adjunct Professor
Department of Anesthesiology (School of Medicine)

Location:
Room 729A, School of Nursing Building
Phone:
410-706-8244
Email:
colloca@umaryland.edu
Personal Website

Education

  • MD, Neurophysiology, University Magna Graecia of Catanzaro School of Medicine
  • PhD, University of Turin Medical School
  • MS, Master in Bioethics, University of Turin

Contracts, Fellowships, Grants, and Sponsored Research

  • Title:
    Chronic orofacial pain: genetics, cognitive-emotional factors, and endogenous modulatory systems
    Sponsoring Organization:
    NIH/NIDCR
    Role:
    Principal
  • Title:
    RO1 NS096007-01, ‘Neural Activity and Ratings for the Expectation of Pain’
    Sponsoring Organization:
    NIH
    Role:
    Co-Principal
  • Title:
    3rd International conference of The Society for Interdisciplinary Placebo StudiesSIPS - Harnessing placebo mechanisms for optimal pain management and treatment of alcohol and other drug use disorders
    Sponsoring Organization:
    NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM (NIAAA)
    Role:
    Co-Principal
  • Title:
    Neural correlates of hypoalgesia driven by observation
    Sponsoring Organization:
    National Center for Complementary & Integrative Health (NCCIH) of the National Institutes of Health (NIH)
    Role:
    Principal

Research Interests

  • Dr. Luana Colloca has conducted pioneering ground-breaking studies that have advanced scientific understanding of the psychoneurobiological bases of endogenous systems for pain modulation in humans. As a result, Dr. Colloca has developed an international reputation as a leading scientist for advancing knowledge of the neurobiological mechanisms of placebo and nocebo effects with an integrative approach including psychopharmacological, neurobiological and behavioral approaches. Her research has been published in top-ranked international journals including Biological Psychiatry, Pain, JAMA, NEJM and Lancet Neurology. The impact of her innovative work is clear from her impressive citation rate and more than 130 invited lectures. Her research has been also featured on The National Geographic, The New Scientist, Washington Post, Science daily, Boston Globe, The New Yorker Time, Nature, The Guardian, The Wall Street Journal, News and World Reports, COSMOS (Australia), The Australian, and USA Today. Dr. Colloca has been honored with prestigious awards such as the 2017 Wall Patrick International Award from the International Association for Study of Pain and the Dubner Award among other.

Publications

  • Colloca, L. (2019, January (1st Quarter/Winter) 6). The Placebo Effect in Pain Therapies.. Annual review of pharmacology and toxicology, 59, 191-211. doi:10.1146/annurev-pharmtox-010818-021542
  • Honzel, E., Murthi, S., Brawn-Cinani, B., Colloca, G., Kier, C., Varshney, A., et al (2019, February 25). Virtual Reality, Music and Pain: developing the premise for an interdisciplinary approach to pain management.. Pain. doi:10.1097/j.pain.0000000000001539
  • Pattullo, G. G. & Colloca, L. (2019, June 1). The opioid epidemic: could enhancing placebo effects be part of the solution?. British journal of anaesthesia, 122 (6), e209-e210. doi:10.1016/j.bja.2018.11.027
  • Colloca, L., Wang, Y., Martinez, P. E., Christy Chang, Y. P., Ryan, K. A., Hodgkinson, C., et al (2019, May 6). OPRM1 rs1799971 - COMT rs4680 - FAAH rs324420 genes interact with placebo procedures to induce hypoalgesia.. Pain. doi:10.1097/j.pain.0000000000001578
  • Colloca, L. & Howick, J. (2018, January (1st Quarter/Winter) 1). Placebos Without Deception: Outcomes, Mechanisms, and Ethics.. International review of neurobiology, 138, 219-240. doi:10.1016/bs.irn.2018.01.005
  • Colloca, L., Ludman, T., Bouhassira, D., Baron, R., Dickenson, A. H., Yarnitsky, D., et al (2017, February 16). Neuropathic pain.. Nature reviews. Disease primers, 3, 17002. doi:10.1038/nrdp.2017.2
  • Colloca, L. (2017, October (4th Quarter/Autumn) 6). Nocebo effects can make you feel pain.. Science (New York, N.Y.), 358 (6359), 44. doi:10.1126/science.aap8488
  • Colloca, L., Pine, D. S., Ernst, M., Miller, F. G. & Grillon, C. (2016, May 15). Vasopressin Boosts Placebo Analgesic Effects in Women: A Randomized Trial.. Biological psychiatry, 79 (10), 794-802. doi:10.1016/j.biopsych.2015.07.019
  • Colloca, L. & Finniss, D. (2012, February 8). Nocebo effects, patient-clinician communication, and therapeutic outcomes.. JAMA, 307 (6), 567-8. doi:10.1001/jama.2012.115
  • Colloca, L. & Barsky, A. J. (2020, February 6). Placebo and Nocebo Effects.. The New England journal of medicine, 382 (6), 554-561. doi:10.1056/NEJMra1907805

See a full list of published work.

Presentations

  • Year:
    2018
    Title:
    Are placebos the solution? Tackling the opioid epidemic in the next few decades - https://www.youtube.com/watch?v=XPtKdtF05s8
    Conference/Meeting Name:
    TEDx talk University of Maryland
    Sponsoring Organization:
    University of Maryland School of Medicine and School of Nursing
    Location:
    Baltimore United States
  • Year:
    2020
    Title:
    Interview with Sheilah Kast for WYPR Radio - https://www.wypr.org/post/your-brain-pain

Areas of Specialization

  • Acute experimental pain; Brain mapping; Clinical and experimental; Chronic pain; Phenotypes of placebo responders; Placebo effects; Nocebo effects; Pain modulation mechanisms; Temporomandibular Disorders; Virtual Reality mechanisms.

Honors/Awards

  • Name:
    Patrick Wall International Award
    Sponsoring organization:
    International Association for Study of Pain
    Date:
    September 2016
  • Name:
    Stephen Milan Award
    Sponsoring organization:
    TMJA
    Date:
    September 2016

Academic and Professional Activities

University

  • Organization:
    CTSA TL1 Pre- and Postdoctoral Training Program
    Role:
    Director

Professional

  • Organization:
    Special Interest Groups - IASP
    Role:
    President