Cynthia Renn, PhD, RN, FAAN

Cynthia Renn, PhD, RN, FAAN
  • Chair, Pain and Translational Symptom Science
    Pain and Translational Symptom Science
  • Professor
    Organizational Systems and Adult Health
  • Co-Director, Center to Advance Chronic Pain Research
    Pain and Translational Symptom Science
Location:
Room 725A, School of Nursing Building
Phone:
410-706-5736
Location:
Room 725A, UMSON
Email:

Education

  • BS, Music Education, Indiana University of Pennsylvania, 1983
  • BS, Nursing, York College of Pennsylvania, 1991
  • MS, Acute Care Nurse Practitioner, University of Maryland, Baltimore, 1997
  • PhD, Neuroscience, University of Maryland, Baltimore, 2004

Contracts, Fellowships, Grants, and Sponsored Research

  • Date:
    2016 - 2021
    Title:
    Omics Associated with Self-Management Interventions for Symptoms (OASIS)
    Sponsoring Organization:
    NIH - NINR
    Role:
    Principal
  • Date:
    2018 - 2023
    Title:
    Physiological, psychological, and genomic factors that predict the transition from acute to chronic pain in patients with traumatic lower extremity fracture
    Sponsoring Organization:
    NIH NINR
    Role:
    Principal
  • Title:
    Neurophysiological and transcriptomic predictors of chronic low back pain: towards precision pain management (NEAT Study)
    Sponsoring Organization:
    NIH - NINR
    Role:
    Principal
  • Title:
    Studying the Role of Sensory Neuron Activity, BDNF Expression, and Central Sensitization and the Effects of Curcumin and Exercise on those Processes in Al-induced Arthralgia Using a New Mouse Model
    Sponsoring Organization:
    NIH NINR
    Role:
    Principal

Research Interests

  • Chronic pain of various etiologies. Studying the underlying mechanisms associated with the development and persistence of chronic pain. Both preclinical and clinical research.

Research Activity

  • Duration:
    2012 - Current
    Title:
    Physiological mechanisms underlying aromatase inhibitor-induced arthralgia
    Description:
    We are examining the physiological mechanisms underlying the development and persistence of AIA using a mouse model. We will pursue this question in a clinical study going forward. This is an ongoing investigation. We are writing several manuscripts reporting our preclinical data.
    Status:
    Writing Results
  • Duration:
    2015 - Current
    Title:
    Physiological & psychological mechanisms of chronic pain in lower extremity fracture
    Description:
    We are examining the biobehavioral, psychological, and genetic/genomic predictors of those who will develop chronic pain at the fracture site. This study is ongoing. We submitted an R01 and are awaiting council review.
    Status:
    On-Going

Publications

  • Renn, C. L. & Dorsey, S. G. (2005, July (3rd Quarter/Summer) 1). The physiology and processing of pain: a review.. AACN clinical issues, 16 (3), 277-90; quiz 413-5.
  • Renn, C. L., Lin, L., Thomas, S. & Dorsey, S. G. (2006, July (3rd Quarter/Summer) 31). Full-length tropomyosin-related kinase B expression in the brainstem in response to persistent inflammatory pain.. Neuroreport, 17 (11), 1175-9. doi:10.1097/01.wnr.0000215771.61355.e1
  • Dorsey, S. G., Renn, C. L., Carim-Todd, L., Barrick, C. A., Bambrick, L., Krueger, B. K., et al (2006, July (3rd Quarter/Summer) 6). In vivo restoration of physiological levels of truncated TrkB.T1 receptor rescues neuronal cell death in a trisomic mouse model.. Neuron, 51 (1), 21-8. doi:10.1016/j.neuron.2006.06.009
  • Dorsey, S. G., Leitch, C. C., Renn, C. L., Lessans, S., Smith, B. A., Wang, X. M., et al (2009, July (3rd Quarter/Summer) 1). Genome-wide screen identifies drug-induced regulation of the gene giant axonal neuropathy (Gan) in a mouse model of antiretroviral-induced painful peripheral neuropathy.. Biological research for nursing, 11 (1), 7-16. doi:10.1177/1099800409332726
  • Renn, C. L., Leitch, C. C. & Dorsey, S. G. (2009, October (4th Quarter/Autumn) 29). In vivo evidence that truncated trkB.T1 participates in nociception.. Molecular pain, 5, 61. doi:10.1186/1744-8069-5-61
  • Renn, C. L., Leitch, C. C., Lessans, S., Rhee, P., McGuire, W. C., Smith, B. A., et al (2011, October (4th Quarter/Autumn) 1). Brain-derived neurotrophic factor modulates antiretroviral-induced mechanical allodynia in the mouse.. Journal of neuroscience research, 89 (10), 1551-65. doi:10.1002/jnr.22685
  • Renn, C. L. & Dorsey, S. G. (2011, January (1st Quarter/Winter) 1). From mouse to man: The efficacy of animal models of human disease in genetic and genomic research.. Annual review of nursing research, 29, 99-112.
  • Renn, C. L., Carozzi, V. A., Rhee, P., Gallop, D., Dorsey, S. G. & Cavaletti, G. (2011, April (2nd Quarter/Spring) 26). Multimodal assessment of painful peripheral neuropathy induced by chronic oxaliplatin-based chemotherapy in mice.. Molecular pain, 7, 29. doi:10.1186/1744-8069-7-29
  • Dorsey, S. G., Lovering, R. M., Renn, C. L., Leitch, C. C., Liu, X., Tallon, L. J., et al (2012, January (1st Quarter/Winter) 1). Genetic deletion of trkB.T1 increases neuromuscular function.. American journal of physiology. Cell physiology, 302 (1), C141-53. doi:10.1152/ajpcell.00469.2010
  • Carozzi, V. A., Renn, C. L., Bardini, M., Fazio, G., Chiorazzi, A., Meregalli, C., et al (2013, January (1st Quarter/Winter) 1). Bortezomib-induced painful peripheral neuropathy: an electrophysiological, behavioral, morphological and mechanistic study in the mouse.. PloS one, 8 (9), e72995. doi:10.1371/journal.pone.0072995

See a full list of published work.

Presentations

  • Year:
    2016
    Title:
    Association of acute pain intensity during immediate hospitalization following injury and subsequent chronic pain
    Conference/Meeting Name:
    American Public Health Association Annual Meeting
    Sponsoring Organization:
    APHA
    Location:
    Denver CO United States
  • Year:
    2017
    Title:
    Comparison of quantitative sensory testing and current perception threshold testing results in patients with chronic pain following lower extremity fracture and healthy controls
    Conference/Meeting Name:
    American Pain Society Annual Scientific Meeting
    Sponsoring Organization:
    APS
    Location:
    Pittsburgh PA United States
  • Year:
    2018
    Title:
    Cited in Scopus: 0Change in pain scores following administration of analgesics in patients with lower extremity fractures
    Conference/Meeting Name:
    American Pain Society Annual Meeting Scientific
    Sponsoring Organization:
    American Pain Society
    Location:
    Anaheim CA United States

Areas of Specialization

  • Preclinical and Clinical Studies of Chronic Pain

Primary Teaching Areas

  • Research
    Physiology
    Pain

Academic and Professional Activities

University

  • Date:
    2018 - 2020
    Organization:
    Faculty Council
    Role:
    Committee Member
  • Date:
    2016 - 2019
    Organization:
    Faculty Senate
    Role:
    Committee Member
  • Date:
    2016 - 2019
    Organization:
    PhD Curriculum Committee
    Role:
    Committee Member & Chair 2017-2018
  • Date:
    2014 - Current
    Organization:
    Center to Advance Chronic Pain Research
    Role:
    Executive Committee Member

Professional

  • Date:
    2018 - 2018
    Organization:
    NIH - NINR P29/P30 Study Section (ZNR1 REV M34)
    Role:
    Grant Reviewer/Referee
  • Date:
    2018 - 2018
    Organization:
    Medical Research Council, MRC IIB Grant Review
    Role:
    Grant Reviewer/Referee
  • Date:
    2017 - 2017
    Organization:
    NIH -NCI
    Role:
    Grant Reviewer/Referee
  • Date:
    2020 - 2021
    Organization:
    Nursing Research
    Role:
    Manuscript Reviewer/Referee
  • Date:
    2016 - Current
    Organization:
    Supportive Care in Cancer
    Role:
    Manuscript Reviewer/Referee
  • Date:
    2016 - Current
    Organization:
    Nursing Outlook
    Role:
    Manuscript Reviewer/Referee
  • Date:
    2020 - 2021
    Organization:
    Neuroscience Letters
    Role:
    Manuscript Reviewer/Referee
  • Date:
    2016 - Current
    Organization:
    Journal of Neurosciences in Rural Practice
    Role:
    Manuscript Reviewer/Referee
  • Date:
    2016 - Current
    Organization:
    Journal of Neurosciences in Rural Practice
    Role:
    Manuscript Reviewer/Referee

Public

  • Date:
    2017 - Current
    Organization:
    Committee to Establish Burdick Dog Park in Baltimore City
    Role:
    Committee Member