Lynn Oswald, PhD, RN

Associate Professor, FCH
Address: 555B
Phone Number: 410-706-0928
oswald@umaryland.edu

Education

  • Postdoctoral Fellowship, Psychoneuroendocrinology/Substance Abuse, Johns Hopkins School of Medicine, Baltimore, MD
  • PhD, Biomedical Sciences, Graduate School of Biomedical Sciences, University of Texas Health Science Center, Houston, TX
  • MSN, Psychiatric-Mental Health Nursing, University of Texas Health Science Center, Houston, TX
  • BS, Nursing, University of Wisconsin, Madison, WI

Research

  • Oswald, L. (PI). Conditional Performance Imaging Pilot Study. University of Maryland DRIF funds (2012 – 2013)
  • Oswald, L. (PI). Conditional Performance Assessment Study (Pilot). University of Maryland DRIF funds (2010 – 2011)
  • Oswald, L. (PI). NIH/NIDA, 1R01DA022433: Imaging Research on Impulsivity, Stress and Drug Abuse. Total costs: $3,014,585 (2008 – 2014)
  • Wand, G. (PI), Oswald (Co-I among others). NIH/NIAAA, R01AA010158: Hypothalamic/Pituitary/Adrenal Axis and Alcoholism. Total costs: $2,354,776 (2001 – 2006)
  • Oswald, L. (Postdoctoral Fellow). NIH/NIAAA, F32 AA13681: Stress, Dopamine, HPA axis, and Alcohol Sensitivity. Total costs: $82, 532 (2002 – 2004)
  • Oswald, L (Predoctoral Fellow). NIH/NIDA, F31 DA05962: Research on Individual Sensitivity to Benzodiazepines. Total costs: $37,152 (1999 – 2001)

Research Interests

  • Interrelationships among neurobiological (hormonal stress responses, brain function), behavioral (risk-taking and impulsivity), and environmental (stress, childhood trauma) risks for substance abuse and other stress-related disorders

Selected Publications

  • Oswald, L.M., Wand, G.S., Kuwabara, H., Wong, D.F., Brasic, J.R. (2016). Preliminary examination of the role of striatal dopamine functions in risk-taking behavior in binge drinkers. Intrinsic Activity 4, Suppl. 2.
  • Oswald, L.M. and Wand, G.S. (2016).  Comments and controversies:  Piecing together the neurobiology of decision-making,  Neuroimage 125, 1096-1098. PMID: 26285077. 5 year impact factor 6.797
  • Oswald, L.M., Wand, G.S., Wong, D.F., Brown, C.H., Kuwabara, H., Brasic, J.R. (2015). Risky Decision-Making and Ventral Striatal Dopamine Responses to Amphetamine: A Positron Emission Tomography [11C]Raclopride Study in Healthy Adults, Neuroimage 113, 26-36.  PMID: 25795343. 5 year impact factor 6.797
  • Oswald, L.M., Wand, G.S., Kuwabara, H., Wong, D.F., Zhu, S., Brasic, J.R. (2014). History of childhood adversity is positively associated with ventral striatal dopamine responses to amphetamine. Psychopharmacology, 231 (12), 2417-33. PMCID: PMC4040334. 5 year impact factor 3.752
  • Oswald, L.M., Wand, G.S., Zhu, S., Selby, V. (2013). Volunteerism and self-selection bias in human positron emission tomography research. Brain Imaging and Behavior, 7, 163–176. PMCID: PMC3594082. 5 year impact Factor 4.159
  • Oswald, L.M., Wong, D.F., Zhou, Y., Kumar, A., Brasic, J., Alexander, M., Ye, W., Kuwabara, H., Hilton, J., Wand, G.S. (2007). Impulsivity and chronic stress are associated with striatal dopamine release and subjective responses to amphetamine. Neuroimage, 36: 153-166. 5 year impact factor 6.797
  • Wand, G.S., Oswald, L.M., McCaul, M.E., Wong, D.F., Johnson, E., Zhou, Y., Kuwabara, H., Kumar, A. (2007). Association of amphetamine-induced ventral striatal dopamine release and cortisol responses to psychological stress. Neuropsychopharmacology, 32: 2310-2320. PMID: 17342167. Impact factor 6.399
  • Munro, C.A., McCaul, M.E., Oswald, L.M., Wong, D.F., Zhou, Y., Brasic, J., Kuwabara, H., Kumar, A., Alexander, M., Ye, W., Wand, G.S. (2006). Striatal dopamine release and family history of alcoholism. Alcoholism: Clinical and Experimental Research, 30: 1143-1151. Impact factor 2.829
  • Uhart, M., Chong, R., Oswald, L.M., Lin, P.I., Wand, G.S. (2006). Gender differences in hypothalamic-pituitary-adrenal (HPA) axis reactivity. Psychoneuroendocrinology, 31: 642-652. 5 year impact factor 5.183
  • Oswald, L.M., Zandi, P., Nestadt, G., Potash, J.B., Kalaydijian, A.E., Wand, G.S. (2006). Relationship between cortisol responses to stress and personality. Neuropsychopharmacology, 31: 1583-1591. PMID: 16407895. Impact factor 6.399
  • Munro, C.A., McCaul, M.E., Wong, D.F., Oswald, L.M., Zhou, Y., Brasic, J., Kuwabara, H., Kumar, A., Alexander, M., Ye, W., Wand, G.S. (2006). Sex differences in striatal dopamine release in healthy adults. Biological Psychiatry, 59: 966-74. Impact factor 11.212
  • Chong, M.D., Oswald, L.M., Yang, X., Uhart, M., Lin, P.I., Wand, G.S. (2006). The mu opioid receptor polymorphism A118G predicts cortisol responses to naloxone and stress. Neuropsychopharmacology, 31: 204-211. PMID: 16123758. Impact factor 6.399
  • Oswald, L.M., Wong, D.F., McCaul, M., Zhou, Y., Kuwabara, H., Choi, L., Brasic, J., Wand, G.S. (2005). Relationships among ventral striatal dopamine release, cortisol secretion, and subjective responses to amphetamine. Neuropsychopharmacology, 30, 821-832. PMID: 15702139. Impact factor 6.399
  • Oswald, L.M., McCaul, M., Choi, L., Yang, X., Wand, G.S. (2004). Catechol-O-methyltransferase polymorphism alters hypothalamic-pituitary-adrenal axis responses to naloxone: A preliminary report. Biological Psychiatry 55:102-105. Impact factor 11.212
  • Oswald, L.M., Wand, G.S. (2004). Opioids and alcoholism. Physiology and Behavior, 81: 339-358. 5 year impact factor 2.986
  • Oswald, L.M., Mathena, J.R., Wand, G.S. (2004). Comparison of HPA axis hormonal responses to naloxone vs. psychologically-induced stress. Psychoneuroendocrinology, 29, 371-388. 5 year impact factor 5.183
  • Oswald, L.M., Roache, J.D., Rhoades, H.M. (1999). Predictors of individual differences in alprazolam self-medication. Experimental and Clinical Psychopharmacology, 4, 379-390. 5 year impact factor 2.658
  • Oswald, L.M., Walker, G.C., Krajewski, K.J., Reilly, E.L. (1994). General and specific locus of control in cocaine abusers. Journal of Substance Abuse, 6, 179-190

Primary Teaching Areas

  • Biostatistics for Evidence-Based Practice
  • Neurophysiology of Mental Disorders
  • Research and Evidenced-Based Practice

Academic & Professional Activities

  • 2016:  Ad hoc grant reviewer for the Italian Ministry of Health (MOH), Department of Public Health and Innovation International Evaluation Process 2014-2015 Grant Call.
  • 2015:  Member NIH Special Emphasis Panel/Scientific Review Group 2015/10 ZRG1 PSE-D (51) R for RFA-DA-15-015 Adolescent Brain Cognitive Development (ABCD) Study research projects (U01). This initiative will fund the largest multisite, longitudinal cohort study ever conducted on the short- and long-term neurodevelopmental and behavioral effects of substance use in adolescents.
  • 2014:  Ad hoc grant reviewer for the Italian Ministry of Health (MOH), Department of Public Health and Innovation International Evaluation Process 2012-2013 Grant Call.
  • 2013:  Ad hoc grant reviewer for the Italian Ministry of Health (MOH), Department of Public Health and Innovation International Evaluation Process 2011-2012 Grant Call.
  • 2012:  Member NIH Special Emphasis Panel/Scientific Review Group 2012/05 ZRG1 EMNR-Q (50) R for P50 applications, RFA-OD-11-003 Specialized Centers of Interdisciplinary Research (SCOR) on Sex Differences.
  • 2011:  Member Scientific Review Group, NIDA Imaging Science Track Award for Research Transition (I/START) [R03], ZDA1 GXM-A (02) 1
  • 2010:  Member Scientific Review Group, NIDA Imaging Science Track Award for Research Transition (I/START) [R03], ZDA1 GXM-A (03) 1
  • 2010:  Member Scientific Review Group, NIDA Imaging Science Track Award for Research Transition (I/START) [R03], ZDA1 GXM-A (04) 1
  • 2009:  Member Scientific Review Group, NIDA Imaging Science Track Award for Research Transition (I/START) [R03], ZDA1 GXM-A (02) 1
  • 2012-present:  Member, UMB-SON Center for biology and Behavior across the Lifespan (BBAL)
  • 2015-present:  Member, UMB-SOM Brain Science Research Consortium Unit (BSRCU)
  • 2005-2006:  Member, Nursing Expert Panel, NIAAA Nursing Education Curriculum in the Prevention and Treatment of Alcohol Problems
  • 2009-present:  Member, College on Problems of Drug Dependence (CPDD)
  • 2007-2014:  Member, Southern Nursing Research Society (SNRS)    
  • 2002-present:  Member, Research Society on Alcoholism (RSA)                        
  • 2003-2005:  Member, International Society for Biomedical Research on Alcoholism (ISBRA) 
  • 1996-2001:  Member, Advisory Panel for the UT-Houston Health Science Center School of Nursing, Psychiatric/Mental Health Nursing Master’s Track, Addictions Focus Program
  • Reviewer for the following journals:  Psychopharmacology, NeuroImage, Schizophrenia Bulletin, Archives of General Psychiatry, Biological Psychiatry, International Journal of Behavioral Medicine, Current Opinion in Behavioral Sciences, Perspectives on Addictions Nursing